Updates

The following table lists all updates to the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK (Red Book) and its constituent Donor Selection Guidelines (DSGs).

For updates specific to each set of guidelines, see the relevant Updates page:

• Geographical Disease Risk Index
• Whole blood and components
• Tissue (deceased donors)
• Tissue (live donors)
• Bone marrow and peripheral blood stem cells
• Cord blood
• Red Book

The linked Change Notification documents were issued to the UK Blood and Tissue Services (UKBTS) to indicate upcoming changes. Please note that the dates listed below indicate the formal publication of updated guidelines on the website. For changes pending publication, see Upcoming changes to the guidelines.

The implementation of these guideline changes is the responsibility of each UKBTS and may vary accordingly.

Change number	Title	Updated	Guidelines affected
Change notification number 27-2026	Title Functional neurological disorder (PDF only, 167KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 28-2026	Title Parathyroid disease (PDF only, 169KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 29-2026	Title Polyendocrine metabolic ovarian syndrome (PDF only, 272KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 32-2026	Title Medication and donor eligibility (PDF only, 239KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 33-2026	Title Lymphopenia and platelet apheresis donation (PDF only, 203KB)	Update date 17 September 2026	Guidelines affected Red book
Change notification number 30-2026	Title Reversible cerebral vasoconstriction syndrome (PDF only, 190KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 34-2026	Title Correction - Saudi Arabia (PDF only, 190KB)	Update date 17 September 2026	Guidelines affected Geographical index
Change notification number 31-2026	Title Transgender and non-binary individuals (PDF only, 213KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 22-2026	Title Cold-stored Platelets, in Additive Solution and Plasma, Leucocyte Depleted (PDF only, 203KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 23-2026	Title Platelets, Apheresis, in Additive Solution and Plasma, Leucocyte Depleted (PDF only, 253KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 24-2026	Title Updates to consent guidance (chapters 6 and 8) (PDF only, 203KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 25-2026	Title Microbiology tests for donors and donations (chapter 9) (PDF only, 459KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 20-2026	Title VHF risks in the GDRI (PDF only, 243KB)	Update date 11 August 2026	Guidelines affected Geographical index
Change notification number 12-2026	Title Mosquito-borne viruses (PDF only, 454KB)	Update date 11 August 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 13-2026	Title Kidney and bladder disease (PDF only, 455KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 17-2026	Title Eligibility of blood donors undergoing acupuncture (PDF only, 287KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 18-2026	Title Chikungunya vaccination (PDF only, 146KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 19-2026	Title Donation prior to hazardous activities (PDF only, 199KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 15-2026	Title Alopecia treatments (PDF only, 241KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 16-2026	Title Antithrombotic treatments (PDF only, 209KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 14-2026	Title Non-alcoholic fatty liver disease (NAFLD) (PDF only, 184KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 21-2026	Title Coronavirus infection (PDF only, 238KB)	Update date 11 August 2026	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 11-2026	Title Platelets in Additive Solution and Plasma for Neonatal Use, Leucocyte Depleted (PDF only, 192KB)	Update date 28 May 2026	Guidelines affected Red book
Change notification number 09-2026	Title Changes to be introduced on the new JPAC website (PDF only, 864KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 10-2026	Title Changes to entries in the GDRI and DSGs (PDF only, 418KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood