Updates

The following table lists all updates to the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK (Red Book) and its constituent Donor Selection Guidelines (DSGs).

For updates specific to each set of guidelines, see the relevant Updates page:

• Geographical Disease Risk Index
• Whole blood and components
• Tissue (deceased donors)
• Tissue (live donors)
• Bone marrow and peripheral blood stem cells
• Cord blood
• Red Book

The linked Change Notification documents were issued to the UK Blood and Tissue Services (UKBTS) to indicate upcoming changes. Please note that the dates listed below indicate the formal publication of updated guidelines on the website. For changes pending publication, see Upcoming changes to the guidelines.

The implementation of these guideline changes is the responsibility of each UKBTS and may vary accordingly.

Change number	Title	Updated	Guidelines affected
Change notification number 06-2025	Title Endoscopy (PDF only, 196KB)	Update date 30 April 2025	Guidelines affected Whole blood
Change notification number 07-2025	Title Memorial Tattoos (PDF only, 174KB)	Update date 30 April 2025	Guidelines affected Whole blood
Change notification number 08-2025	Title Topical Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (PDF only, 176KB)	Update date 30 April 2025	Guidelines affected Whole blood
Change notification number 09-2025	Title Table of Immunisations (PDF only, 578KB)	Update date 30 April 2025	Guidelines affected Whole bloodTissue (live)Tissue (deceased)Cord bloodBone marrow
Change notification number 04-2025	Title Clinical supervision at donor sessions (PDF only, 267KB)	Update date 28 February 2025	Guidelines affected Red book
Change notification number 03-2025	Title Hepatitis C testing of donors transfused before 1996 (IBI update) (PDF only, 211KB)	Update date 17 February 2025	Guidelines affected Whole blood
Change notification number 02-2025	Title Human Plasma for Fractionation, Cryoprecipitate Depleted, Leucocyte Depleted (PDF only, 230KB)	Update date 25 January 2025	Guidelines affected Red book
Change notification number 01-2025	Title Removal of Dengue risk in Italy (PDF only, 196KB)	Update date 17 January 2025	Guidelines affected Geographical index
Change notification number 45-2024	Title Hepatitis A (PDF only, 300KB)	Update date 26 November 2024	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 46-2024	Title COVID-19 vaccination (PDF only, 288KB)	Update date 26 November 2024	Guidelines affected Whole blood
Change notification number 47-2024	Title Topical Anti-Androgens (PDF only, 175KB)	Update date 26 November 2024	Guidelines affected Whole blood
Change notification number 48-2024	Title Haemolytic Anaemia (PDF only, 238KB)	Update date 26 November 2024	Guidelines affected Whole blood
Change notification number 49-2024	Title Monoclonal Antibody Therapies (PDF only, 264KB)	Update date 26 November 2024	Guidelines affected Whole blood
Change notification number 51-2024	Title Migraine and Topiramate (PDF only, 224KB)	Update date 26 November 2024	Guidelines affected Whole blood
Change notification number 52-2024	Title WNV in France (PDF only, 649KB)	Update date 26 November 2024	Guidelines affected Geographical index
Change notification number 50-2024	Title Updates in the GDRI (PDF only, 242KB)	Update date 28 October 2024	Guidelines affected Geographical index
Change notification number 27-2024	Title Platelet Disorders (PDF only, 152KB)	Update date 7 October 2024	Guidelines affected Whole blood
Change notification number 28-2024	Title Donor Adverse Events Severity Grading (PDF only, 266KB)	Update date 7 October 2024	Guidelines affected Red book
Change notification number 30-2024	Title Cerebrovascular Disease and Intracranial Haemorrhage (PDF only, 227KB)	Update date 7 October 2024	Guidelines affected Whole blood
Change notification number 43-2024	Title Links to Immunodeficiency entry in WB-DSG (PDF only, 111KB)	Update date 7 October 2024	Guidelines affected Whole blood
Change notification number 44-2024	Title Dengue in France, Italy, Iran and UAE (PDF only, 708KB)	Update date 7 October 2024	Guidelines affected Geographical index
Change notification number 31-2024	Title Acute Infection (PDF only, 145KB)	Update date 13 August 2024	Guidelines affected Bone marrow
Change notification number 32-2024	Title Necrotising Fasciitis (PDF only, 101KB)	Update date 13 August 2024	Guidelines affected Tissue (deceased)
Change notification number 33-2024	Title Tuberculosis (PDF only, 111KB)	Update date 13 August 2024	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 34-2024	Title Vitamin Treatment (PDF only, 59KB)	Update date 13 August 2024	Guidelines affected Bone marrow