Updates

The following table lists all updates to the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK (Red Book) and its consitituent Donor Selection Guidelines (DSGs).

The linked Change Notification documents are issued to the UK Blood and Tissue Services (UKBTS) to indicate upcoming changes. Please note that the dates listed below indicate the formal publication of updated guidelines on the website. The implementation of these guideline changes is the responsibility of each UKBTS and may vary accordingly.

Change number	Title	Updated	Guidelines affected
Change notification number 09-2026	Title Changes to be introduced on the new JPAC website (PDF only, 864KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 10-2026	Title Changes to entries in the GDRI and DSGs (PDF only, 418KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 08-2026	Title VHF risk in Ethiopia (PDF only, 194KB)	Update date 23 March 2026	Guidelines affected Geographical index
Change notification number 02-2026	Title Removal of vCJD risk from blood component labels (PDF only, 183KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 03-2026	Title Red Book Chapter 23 (PDF only, 869KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 04-2026	Title Red Book Chapter 3.4 (PDF only, 315KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 05-2026	Title Bleeding Disorder (PDF only, 283KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 06-2026	Title Transgender and Non-Binary Individuals (PDF only, 210KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 07-2026	Title Testosterone Replacement Therapy (PDF only, 339KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 01-2026	Title Introduction of seasonal risk for Tropical Viruses (PDF only, 776KB)	Update date 19 January 2026	Guidelines affected Geographical index
Change notification number 36-2025	Title Removal of malaria risk in East Timor and Suriname (PDF only, 228KB)	Update date 8 December 2025	Guidelines affected Geographical index
Change notification number 37-2025	Title VHF risk in Ethiopia (PDF only, 195KB)	Update date 8 December 2025	Guidelines affected Geographical index
Change notification number 38-2025	Title Red Cells for Neonates and Infants, Leucocyte Depleted, Washed (PDF only, 255KB)	Update date 8 December 2025	Guidelines affected Red book
Change notification number 34-2025	Title Dengue Virus risks in the GDRI (PDF only, 327KB)	Update date 6 December 2025	Guidelines affected Geographical index
Change notification number 35-2025	Title GDRI Preliminaries (PDF only, 382KB)	Update date 6 November 2025	Guidelines affected Geographical index
Change notification number 30-2025	Title Hepatitis A (PDF only, 205KB)	Update date 30 October 2025	Guidelines affected Bone marrowCord blood
Change notification number 31-2025	Title Tropical Viruses (PDF only, 194KB)	Update date 13 October 2025	Guidelines affected Bone marrow
Change notification number 32-2025	Title Sexually Transmitted Disease (PDF only, 197KB)	Update date 13 October 2025	Guidelines affected Bone marrowTissue (deceased)Tissue (live)Cord blood
Change notification number 33-2025	Title France and Italy (PDF only, 778KB)	Update date 13 October 2025	Guidelines affected Geographical index
Change notification number 20-2025	Title Chronic Fatigue Syndrome (PDF only, 260KB)	Update date 13 October 2025	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 21-2025	Title Transgender and Non-Binary Individuals (PDF only, 226KB)	Update date 13 October 2025	Guidelines affected Tissue (live)Tissue (deceased)
Change notification number 22-2025	Title Injectable Pre-Exposure Prophylaxis (PrEP) for HIV prevention (PDF only, 293KB)	Update date 13 October 2025	Guidelines affected Tissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 16-2025	Title Eye Disease (PDF only, 190KB)	Update date 13 October 2025	Guidelines affected Tissue (deceased)
Change notification number 17-2025	Title Kidney Disease (PDF only, 180KB)	Update date 13 October 2025	Guidelines affected Tissue (deceased)
Change notification number 18-2025	Title Hormone Replacement and Sex Hormone Therapy (PDF only, 231KB)	Update date 13 October 2025	Guidelines affected Tissue (deceased)Tissue (live)