Updates

The following table lists all updates to the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK (Red Book) and its constituent Donor Selection Guidelines (DSGs).

For updates specific to each set of guidelines, see the relevant Updates page:

• Geographical Disease Risk Index
• Whole blood and components
• Tissue (deceased donors)
• Tissue (live donors)
• Bone marrow and peripheral blood stem cells
• Cord blood
• Red Book

The linked Change Notification documents were issued to the UK Blood and Tissue Services (UKBTS) to indicate upcoming changes. Please note that the dates listed below indicate the formal publication of updated guidelines on the website. For changes pending publication, see Upcoming changes to the guidelines.

The implementation of these guideline changes is the responsibility of each UKBTS and may vary accordingly.

Change number	Title	Updated	Guidelines affected
Change notification number 35-2026	Title Bleeding disorder (PDF only, 336KB)	Update date 6 October 2026	Guidelines affected Bone marrowCord blood
Change notification number 36-2026	Title Fertility (PDF only, 217KB)	Update date 6 October 2026	Guidelines affected Bone marrow
Change notification number 37-2026	Title Osteoarthritis (PDF only, 209KB)	Update date 6 October 2026	Guidelines affected Bone marrowCord blood
Change notification number 38-2026	Title Parvovirus B19 (PDF only, 202KB)	Update date 6 October 2026	Guidelines affected Bone marrowCord blood
Change notification number 39-2026	Title Snake bites (PDF only, 245KB)	Update date 6 October 2026	Guidelines affected Bone marrowCord blood
Change notification number 40-2026	Title Donor weight and weight loss medication (PDF only, 291KB)	Update date 6 October 2026	Guidelines affected Tissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 41-2026	Title Immunosuppression and monoclonal antibody treatments (PDF only, 339KB)	Update date 6 October 2026	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 42-2026	Title Raynaud's syndrome (PDF only, 210KB)	Update date 6 October 2026	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 43-2026	Title Whole hearts for tissue allografts (PDF only, 195KB)	Update date 6 October 2026	Guidelines affected Tissue (deceased)
Change notification number 44-2026	Title Post-mortem retrieval time limits for deceased tissue donors (PDF only, 200KB)	Update date 6 October 2026	Guidelines affected Red book
Change notification number 46-2026	Title Mosquito-borne virus risks in Italy and the Netherlands (PDF only, 552KB)	Update date 2 October 2026	Guidelines affected Geographical index
Change notification number 47-2026	Title Viral haemorrhagic fever risk in Uganda (PDF only, 207KB)	Update date 2 October 2026	Guidelines affected Geographical index
Change notification number 45-2026	Title France and USA (PDF only, 880KB)	Update date 25 September 2026	Guidelines affected Geographical index
Change notification number 27-2026	Title Functional neurological disorder (PDF only, 167KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 28-2026	Title Parathyroid disease (PDF only, 169KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 29-2026	Title Polyendocrine metabolic ovarian syndrome (PDF only, 272KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 32-2026	Title Medication and donor eligibility (PDF only, 239KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 33-2026	Title Lymphopenia and platelet apheresis donation (PDF only, 203KB)	Update date 17 September 2026	Guidelines affected Red book
Change notification number 30-2026	Title Reversible cerebral vasoconstriction syndrome (PDF only, 190KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 34-2026	Title Correction - Saudi Arabia (PDF only, 190KB)	Update date 17 September 2026	Guidelines affected Geographical index
Change notification number 31-2026	Title Transgender and non-binary individuals (PDF only, 213KB)	Update date 17 September 2026	Guidelines affected Whole blood
Change notification number 22-2026	Title Cold-stored Platelets, in Additive Solution and Plasma, Leucocyte Depleted (PDF only, 203KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 23-2026	Title Platelets, Apheresis, in Additive Solution and Plasma, Leucocyte Depleted (PDF only, 253KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 24-2026	Title Updates to consent guidance (chapters 6 and 8) (PDF only, 203KB)	Update date 19 August 2026	Guidelines affected Red book
Change notification number 25-2026	Title Microbiology tests for donors and donations (chapter 9) (PDF only, 459KB)	Update date 19 August 2026	Guidelines affected Red book