Updates

The following table lists all updates to the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK (Red Book) and its constituent Donor Selection Guidelines (DSGs).

For updates specific to each set of guidelines, see the relevant Updates page:

• Geographical Disease Risk Index
• Whole blood and components
• Tissue (deceased donors)
• Tissue (live donors)
• Bone marrow and peripheral blood stem cells
• Cord blood
• Red Book

The linked Change Notification documents were issued to the UK Blood and Tissue Services (UKBTS) to indicate upcoming changes. Please note that the dates listed below indicate the formal publication of updated guidelines on the website. For changes pending publication, see Upcoming changes to the guidelines.

The implementation of these guideline changes is the responsibility of each UKBTS and may vary accordingly.

Change number	Title	Updated	Guidelines affected
Change notification number 20-2026	Title VHF risks in the GDRI (PDF only, 243KB)	Update date 11 August 2026	Guidelines affected Geographical index
Change notification number 12-2026	Title Mosquito-borne viruses (PDF only, 454KB)	Update date 11 August 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 13-2026	Title Kidney and bladder disease (PDF only, 455KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 17-2026	Title Eligibility of blood donors undergoing acupuncture (PDF only, 287KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 18-2026	Title Chikungunya vaccination (PDF only, 146KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 19-2026	Title Donation prior to hazardous activities (PDF only, 199KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 15-2026	Title Alopecia treatments (PDF only, 241KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 16-2026	Title Antithrombotic treatments (PDF only, 209KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 14-2026	Title Non-alcoholic fatty liver disease (NAFLD) (PDF only, 184KB)	Update date 11 August 2026	Guidelines affected Whole blood
Change notification number 21-2026	Title Coronavirus infection (PDF only, 238KB)	Update date 11 August 2026	Guidelines affected Tissue (deceased)Tissue (live)
Change notification number 11-2026	Title Platelets in Additive Solution and Plasma for Neonatal Use, Leucocyte Depleted (PDF only, 192KB)	Update date 28 May 2026	Guidelines affected Red book
Change notification number 09-2026	Title Changes to be introduced on the new JPAC website (PDF only, 864KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 10-2026	Title Changes to entries in the GDRI and DSGs (PDF only, 418KB)	Update date 1 May 2026	Guidelines affected Geographical indexWhole bloodTissue (deceased)Tissue (live)Bone marrowCord blood
Change notification number 08-2026	Title VHF risk in Ethiopia (PDF only, 194KB)	Update date 23 March 2026	Guidelines affected Geographical index
Change notification number 02-2026	Title Removal of vCJD risk from blood component labels (PDF only, 183KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 03-2026	Title Red Book Chapter 23 (PDF only, 869KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 04-2026	Title Red Book Chapter 3.4 (PDF only, 315KB)	Update date 17 February 2026	Guidelines affected Red book
Change notification number 05-2026	Title Bleeding Disorder (PDF only, 283KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 06-2026	Title Transgender and Non-Binary Individuals (PDF only, 210KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 07-2026	Title Testosterone Replacement Therapy (PDF only, 339KB)	Update date 17 February 2026	Guidelines affected Whole blood
Change notification number 01-2026	Title Introduction of seasonal risk for Tropical Viruses (PDF only, 776KB)	Update date 19 January 2026	Guidelines affected Geographical index
Change notification number 36-2025	Title Removal of malaria risk in East Timor and Suriname (PDF only, 228KB)	Update date 8 December 2025	Guidelines affected Geographical index
Change notification number 37-2025	Title VHF risk in Ethiopia (PDF only, 195KB)	Update date 8 December 2025	Guidelines affected Geographical index
Change notification number 38-2025	Title Red Cells for Neonates and Infants, Leucocyte Depleted, Washed (PDF only, 255KB)	Update date 8 December 2025	Guidelines affected Red book
Change notification number 34-2025	Title Dengue Virus risks in the GDRI (PDF only, 327KB)	Update date 6 December 2025	Guidelines affected Geographical index