Familial pseudohyperkalaemia (FP) - Whole blood and components

Essential information

Obligatory

Must not donate.

Discretionary

If the donation will not be used to manufacture red cell components for intrauterine transfusion (IUT) or transfusion to neonates and infants, accept.

Supporting information

See if relevant

Familial pseudohyperkalaemia (FP) is a red cell disorder characterised by altered permeability of the red cell membrane. This is an asymptomatic condition which causes increased leakage of potassium from red cells when stored at refrigerated temperatures. High levels of potassium in stored red cell units are a particular risk for transfusion recipients less than 1 year of age.

The most common FP variant affects about 1 in 400 of the UK donor population (although it is less common in donors from non-European ethnic groups).

Reason for change:

This is a new entry.

Version details:

WB-DSG Edition 203 Release 44 (03 September 2019)