Whole blood and components
The Whole Blood and Components Donor Selection Guidelines (WB-DSG) form a constituent part of chapter 3 of the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK.
They apply to donors giving whole blood or blood components, including red cells, platelets, plasma and granulocytes, and are for healthcare professionals trained in their use.
View the guidelines
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A to Z
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Updates
View all WB-DSG updates
Additional resources
Using these guidelines
Learn how to use and apply the WB-DSG
Source files
Download an offline copy of the WB-DSG
Drugs and platelet donation
View the index of drugs that can alter platelet function and may require a donor deferral
Appendices
Appendix 1
Estimated blood volume for female donors
Appendix 2
Immunisations
Appendix 3
Maximum permitted extracorporeal volume
Appendix 4
Management of post donation illness
Latest updates
| Change number | Title | Updated | Guidelines affected | Release |
|---|---|---|---|---|
| 27-2026 | Functional neurological disorder (PDF only, 167KB) | 17 September 2026 |
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| 28-2026 | Parathyroid disease (PDF only, 169KB) | 17 September 2026 |
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| 29-2026 | Polyendocrine metabolic ovarian syndrome (PDF only, 272KB) | 17 September 2026 |
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| 32-2026 | Medication and donor eligibility (PDF only, 239KB) | 17 September 2026 |
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| 30-2026 | Reversible cerebral vasoconstriction syndrome (PDF only, 190KB) | 17 September 2026 |
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