Inflammatory bowel disease (IBD) - Bone marrow and peripheral blood stem cell

Essential information

Includes

Crohn's disease, ulcerative colitis.

Obligatory

Must not donate.

Discretionary

Refer to Designated Clinical Support Officer. Donor may be considered if in stable remission and off treatment, but should not receive G-CSF, so could donate bone marrow only.

Supporting information

See if relevant

• Infection, general
• Malignancy
• Radiation therapy

Additional information

The cause of these conditions is not fully understood and may include infection. Lesions caused by the disease can increase the risk of bacteria entering the blood stream. There is a risk of adoptive transfer of disease-causing cells which should be discussed with the recipient.

Reason for change:

‘See if Relevant’ section has been added.

Version details:

BM-DSG Edition 203 Release 42 (04 August 2021)