Osteogenesis imperfecta (OI) - Tissue - deceased donors

Essential information

Obligatory

Must not donate.

Discretionary

Skin:

Accept for split skin allografts only; not suitable for the preparation of acellular dermal allografts.

Additional information: Osteogenesis imperfecta is a congenital disorder that results in defective connective tissue due to defects in the genes relating to production of Type I collagen or other connective tissue proteins. Pathology includes bones that fracture easily, loose joints, poor muscle tone and thin, discoloured sclera.