Gout - Bone marrow and peripheral blood stem cell

Essential information

Obligatory

Must not donate.

Discretionary

1. For bone marrow donors:
   Accept.
   
   
2. For PBSC donors:
   Discuss with Designated Clinical Support Officer.
   See Additional information below.

Supporting information

Additional information

Gout is an acute arthritis caused by build-up of uric acid crystals in the joint space. There have been reports of severe exacerbation of gout following administration of G-CSF.

In the interests of donor protection, caution should be exercised before considering donors with gout for PBSC donation. In these circumstances, donors should be counselled about the possibility of exacerbation of their condition and consent to this before proceeding to receive G-CSF.

Affected individuals should be excluded from PBSC donation unless permitted by Designated Clinical Support Officer based on individual risk assessment.

Reason for change:

Exclude affected individuals from donation of PBSC unless permitted by DCSO.

Version details:

BM-DSG Edition 203 Release 54 (29 January 2024)